Job Description

The National University of Singapore invites applications for a Research Assistant to work in Assoc Prof Jan Gruber\'s laboratory to work on basic mechanisms of ageing using C.elegans as the model organism and to support the ageing interventions project. We are a dynamic and growing research group focused on understanding the biology of ageing and developing interventions to improve healthspan and quality of life.

Appointments will be made on a 1 Year contract basis in the first instance, with the possibility of extension.

Purpose of the Post

We are seeking a highly motivated Research Assistant ideally with experience in C. elegans and molecular biology to join our team. The successful candidate will work on a project aimed at developing interventions to improve human healthspan, using C. elegans models. The ideal candidate will have experience with
the following techniques:

• C. elegans handling and maintenance
• Genetics and molecular biology techniques (PCR, cloning, gene expression analysis)
• Microscopy and imaging techniques
• Data analysis and interpretation

Main Duties and Responsibilities * Work independently and as part of a team to design and execute experiments to investigate the molecular mechanisms of ageing and potential interventions using C. elegans as a model organism

• Conduct lifespan assays and physiological assays (e.g., locomotion assays, feeding assays, stress assays) to characterize the effects of ageing interventions
• Use microscopy and imaging techniques to monitor C. elegans phenotypes and perform histological analysis
• Conduct bioinformatics analysis of transcriptomic, proteomic, and genomic data to identify candidate genes and pathways involved in ageing and ageing interventions
• Use statistical analysis software (e.g., R) to analyze and interpret data
• Contribute to the preparation of scientific manuscripts and presentations based on research findings
• Maintain accurate records of experimental procedures, results, and conclusions
• Help train and supervise undergraduate students, new lab members, and interns in laboratory techniques and procedures
• Stay up-to-date with the latest advances in ageing research and contribute to lab meetings and discussions
• Help maintain laboratory equipment and supplies
• Any other duties as assigned by the Reporting Manager

Qualifications

• Bachelor\'s or Master\'s degree in biology, genetics, or a related field
• Minimum of 1 year of experience working with C. elegans or other model organisms
• Strong knowledge of genetics and molecular biology techniques
• Experience with microscopy and imaging techniques
• Experience with bioinformatics analysis, including transcriptomic and genomic data analysis, would be beneficial - but training can be provided.
• Familiarity with statistical analysis software (e.g., R) is desirable
• Excellent organizational skills and attention to detail
• Resourceful, independent, able to learn fast, and work well with others in a team
• Meticulous in record and inventory keeping with excellent organizational skills
• Good written and verbal communication skills

Application

Remuneration will be commensurate with the candidate\'s qualifications and experience. Informal enquiries are welcome and should be made to A/Prof Jan Gruber, at

Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations and full contacts of three (3) referees to this job portal.

We regret that only shortlisted candidates will be notified.

More Information

Location: Kent Ridge Campus
Organization: Yong Loo Lin School of Medicine
Department: Biochemistry
Employee Referral Eligible: No
Job requisition ID: 21538

Times Higher Education