Job Description

The School of Mechanical & Aerospace Engineering (MAE) invites applications for the position of Research Assistant.

The work will be primarily performed at the Clinical Sciences Building in the Novena campus of Lee Kong Chian School of Medicine (LKCMedicine), Nanyang Technological University (NTU) Singapore. The lab focuses on dissecting mechanisms underlying metabolic disorders and their complications, with an overarching goal of unveiling novel therapeutic targets and/or diagnostic biomarkers for metabolic disease/conditions. We are particularly interested in delineating pathways that mediate enhanced formation of neutrophil extracellular traps (NETs) in diabetes, and evaluating the impact of NETs on body systems under metabolic disturbances. We employ a variety of in vitro assays, cell-based approaches, and in vivo murine disease models, in combination with human sample and patient data analysis to address our fundamental research questions. The School and our laboratory strongly support career development activities to help individuals advance in professionalism and achieve their career goals. Individuals with strong enthusiasm in metabolic diseases, inflammation and vascular biology are encouraged to apply.

Key Responsibilities:

Holding and assisting in research projects

Hold independent projects with guidance from the PI/co-PI.

Actively participate in work-related research events (i.e., lab meetings/journal clubs through critical analyses of primary literature and primary data)

Assist other laboratory members in experiments as needed (including cell culture, mouse experiments, mouse specimen collection and fixation, tissue sectioning, histology, Western blotting, microscopy, etc.)

Mouse colony management

Managing mouse breeding to achieve optimal number of animals for experiments

Timely and accurate genotyping to maintain the colony in a cost-effective manner

Procurement and purchasing

Obtain quotations of laboratory equipment, reagents, consumables, mice, etc.

Monitor and project laboratory expenditure

Maintain consumable stocks in the laboratory

General lab management

Establish and maintain laboratory records (including SOPs and risk assessment documents)

Stock laboratory supplies, and aliquot antibodies and reagents for investigator use

Maintain inventories of chemicals, antibodies, etc.

Maintain equipment, lab area and supplies in a neat professional manner

Job Requirements:

Bachelor of Science in Life Sciences, Biomedical Sciences, Biomedical Engineering, or related discipline

Proficiency in animal experiments (including injections and oral gavage) and husbandry. Experience in behavioral studies is a plus

Experienced in infection studies (including culturing bacteria for inoculation)

Experience in tissue histology (e.g., sample sectioning and staining) and confocal microscopy

Benchwork experience including biochemical and molecular assays

At least one-year of working experience in a research laboratory. While candidate should have solid proficiency of the above skillsets, on-the-job training of new techniques will be provided.

Strong enthusiasm in metabolic diseases, inflammation and vascular biology

Meticulous in animal handling and experimentation

Efficient and dependable for laboratory administrative tasks including procurement and establishment of laboratory SOPs

Enjoy and capable in troubleshooting

Be able to work independently and responsibly, as well as a proactive team player with excellent communication (orally and in writing) and interpersonal skills

Be able to set priorities, think critically, organized, and be attentive to details

We regret that only shortlisted candidates will be notified.

Hiring Institution: NTU

Nanyang Technological University