Research Fellow - Bioinformatics / Molecular Epidemiology - Child Health and Development - Singapore Institute for Clinical Sciences
A two-year position at the Singapore Institute for Clinical Sciences is available to a highly-motivated postdoctoral researcher in bioinformatics and/or molecular epidemiology in the area of reproductive, perinatal, and paediatric epidemiology, with particular training and expertise in transcriptomics and epigenomics. The candidate will develop a competitive research portfolio using class-leading multimodal data from up to three longitudinal birth cohort studies (GUSTO, N = ~1200 enrolled; S-PRESTO, N = ~1000 enrolled; and MAMS, N = ~2000 anticipated) in collaboration with local research hospitals, top research universities, government research entities, and a broad network of international collaborators.
The cohorts represent world-class efforts in deep pheno- and geno-typing, with available measures including: clinical characteristics; sociodemographics and spatiotemporal data; parenting and child behaviors; child neurodevelopmental assessment; state-of-the-art brain and body imaging; and numerous -omics (metabolome; (epi)genome; transcriptome; microbiome). A large biorepository (e.g. hair, saliva, urine, blood) has been formed. Details on available data and samples for GUSTO/S-PRESTO can be found at:
The Fellow will work closely with the PI to develop research based on two competitively funded projects:
1. Placental multi-omics linking in vitro fertilization (IVF) and longitudinal child cardiometabolic outcomes. The Fellow will develop and apply methods to investigate mediating mechanisms between IVF and child outcomes utilizing placental multi-omic data (genomic, DNA methylation, and RNAseq).
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