Job Description

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Job Title: Research Fellow (Pharmacology)
Posting Start Date: 14/11/2025
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A Research Fellow position in Associate Prof Gautam Sethi research team, at the Department of Pharmacology, School of Medicine, National University of Singapore.
1.Experimental Work

• Lead the design, execution, and troubleshooting of experiments related to microbial short-chain fatty acids (SCFAs) and their role in mucosal healing in ulcerative colitis.
• Conduct advanced molecular biology, immunology, and microbiome analyses, including metagenomics, metabolomics, and immunophenotyping of colonic tissues.
• Develop and optimize small animal models of colitis to investigate the mechanistic role of SCFA-producing microbes in mucosal repair.
• Perform data analysis using computational pipelines for microbiome and metabolite profiling, ensuring high scientific rigor and reproducibility.
• Contribute to manuscript writing, conference presentations, and preparation of reports for funding agencies.

2. Laboratory and Safety Management

• Ensure adherence to all biosafety, IACUC, and ORMC regulations in conducting animal and microbial experiments.
• Train junior members in proper laboratory safety and animal ethics compliance.

Qualifications
Deliverables and Outcomes

• Drive publications in top-tier peer-reviewed journals arising from the project.
• Support the generation of preliminary data for follow-up grant applications.
• Contribute to achieving the manpower development KPI by training at least two Master's and Honours students during the project period.

Skills Required