Job Description

Career Category Engineering



Senior Engineer \xe2\x80\x93 Process Engineering

Amgen Singapore Manufacturing, Singapore

HOW MIGHT YOU DEFY IMAGINATION?

Amgen is one of the world\xe2\x80\x99s leading independent biotechnology companies. For over 4 decades, Amgen has pioneered biotechnology breakthroughs, to bring state-of-the-art medicines from laboratory to the patient. Amgen has not only discovered and developed innovative human therapeutics, but has invested in cutting edge manufacturing capability and support services to deliver these exciting therapies to medical teams around the world. Japan and Asia Pacific (JAPAC) is the fastest growing region in Amgen. Now we are hiring an Senior Engineer \xe2\x80\x93 Process Engineering in Amgen Singapore Manufacturing.

Senior Engineer \xe2\x80\x93 Process Engineering

Live

What you will do

This role will serve as a process equipment system owner for the Chemical Synthesis API Manufacturing Facility in ASM for the facilities and engineering team.

The role will be a liaison between manufacturing, maintenance, engineering and automation in the troubleshooting and resolution of equipment related issues. Experience in design, qualification, operation, maintenance and improvement of Chemical Synthesis API process equipment will be required to support day to day manufacturing activities as well as to lead improvement projects. Overall Chemical Synthesis processes knowledge will be required to perform complex troubleshooting activities. This role is crucial for Amgen\xe2\x80\x99s success and it will be a key contributor in the ASM- Chemical Synthesis API Manufacturing Facility. This role will partner with vendors/networks to determine innovative opportunities to improve the site\xe2\x80\x99s reliability, efficiency, agility and differentiation.

Main Responsibilities:

Operational Support

• Subject matter expert for process engineering (including process equipment and process automation) to support manufacturing to ensure safety, compliance and sustained operation.
• Lead and participate in the investigation and troubleshooting of process equipment related issues.
• Identify effective recommendation on corrective actions, preventive actions and improvements.
• Effectively communicate and collaborate with cross function stakeholders to address operational challenges and concerns to ensure sustained operation and minimal interruptions.
• Lead process engineering team to provide technical expertise in operational continuous improvement projects or initiatives (yield improvements, risk mitigation, capacity expansion etc.), to translate equipment & automation requirement, propose engineering solutions, collaborate with cross-functional team to deliver.
• Provide technical expertise in new product or new equipment introduction assessment to identify equipment/facility gaps, select new equipment, assess layout/utilities capacity and partner project managers to develop project cost and schedule.
• Lead F&E to participate in technical transfer activities and cross-functional meetings.

Equipment Design & Qualification - Project Engineering:

• Work closely with project managers or site NPI lead to introduce new equipment including development of business case, project charter, user requirement specifications, quality risk assessments, conceptual design, preliminary design, design specifications and detail design.
• Participate in design review and setup up of new asset and associated maintenance plan/spares in Maximo.
• Participate in commissioning and qualification experience activities such as protocol/report review and approval, FAT, SAT, PSSR, automation checkouts and IOQ.
• Work with manufacturing, process development, utilities, facilities, quality assurance and validation departments in developing requirements and recommendations for large and/or highly complex system/facility modifications.
• Work with project managers to complete design and engineering projects within schedule, budget and quality constraints.
• Develop technical solutions to complex problems requiring the regular use of ingenuity and creativity.

Innovation:

• Provide technical expertise to assess emerging industry trends and partner with vendors/networks to determine innovative opportunities to improve reliability, efficiency, agility and differentiation.
• Continuously improve Business Intelligence capabilities (e.g. ability to extract, manipulate, analyze and trend performance data).
• Benchmark equipment performance (e.g. reliability, productivity) and determine improvement plans.
• Assess predictive technologies for implementation.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

Win

What we expect of you

Qualifications

• Doctorate degree OR
• Master\xe2\x80\x99s degree and 2 years of directly related experience OR
• Bachelor\xe2\x80\x99s degree and 4 years of directly related experience OR
• Diploma and 8 years of directly related experience
• Working experience in process engineering team primary in chemical synthesis API manufacturing.
• Established expertise in at least 3 separate areas of engineering technology such as equipment design/operation/maintenance, automation, process engineering, project management and/or validation.
• Working knowledge of high potency active pharmaceutical ingredient (API) processes involving equipment such as Glass lined reactors, Filter dryer, Isolators and critical utilities such as TCU & Scrubber will be an added advantage.
• Experience in validation processes such as generation/execution of Installation/Operation/Performance qualification documentation.
• Demonstrated project management skills (schedule/cost development, facilitation, collaboration, basic project management, completion and follow-up) and application of concepts.
• Problem solving skills requiring the application of scientific and engineering theory and calculations and creative skills in the development of hypotheses and approach.
• Ability to independently determine when additional resources are required to solve problems.
• Foster and maintain relationships with key site and network stakeholders
• Good communications skills, both oral and written, including presentation skills
• Interpersonal and facilitation skills necessary to forge consensus among competing client interests while ensuring objectives are met.
• Strong analytical skills and knowledge of industry trends to identify potential improvement opportunities.
• Ability to combine technical problem-solving skills with business acumen to determine best business solution.
• Knowledge of Operational Excellence practices such as lean manufacturing and lean maintenance.
• Management of contractors and vendors.

Thrive

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates\xe2\x80\x99 professional and personal growth and well-being.

• Vast opportunities to learn and move up and across our global organization
• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

careers.amgen.com

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

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Amgen