The School of Biological Sciences at Nanyang Technological University is seeking a talented and ambitious Senior Postdoctoral Fellow to join the Transcription and Chromatin Regulation Laboratory. The overall goal of our funded projects is to uncover the impact of oncogenic/inflammatory mediators and non-coding RNAs on enhancer regulation, chromatin dynamics and transcriptional control during disease pathogenesis (Nature Cell Biology 2015, 17: 1327-38; PNAS 2016, 113: 14402-07; Nature Communications 2018, 9: 3183).
The successful candidate should demonstrate excellent stem cell biology, epigenetics or RNA biology knowledge and prior expertise in iPSCs and/or tissue organoids generation, cell and molecular biology methods, and a variety of genome editing platforms, as evidenced by a strong publication list (first authored) in the relevant fields. He/she must be able to work in a dynamic and pro-active environment and demonstrate competence in CRISPR epigenome editing, RNA-related assays and genomics work including ChIP-seq and chromosome conformation capture assays.
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The innovative candidate will join a team of experienced molecular and cell biology researchers and computational biologists to perform cutting-edge research in genome editing, induced pluripotent stem cells (iPSCs) disease models and non-coding RNA functions. Our laboratory is focused on developing disease models using iPSCs and tissue organoids to understand epigenomic reprogramming during the progression of cancers and autoimmune diseases.
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