Job Description

PurposeTo supervise, execute and monitor the activities within an assigned work area to ensure reliable and optimal operation of processes, equipment, utility and facility so as to achieve target production levels within the framework of current Good Manufacturing Practice (cGMP), quality, safety, occupational hygiene and environment protection.Key Responsibilities AreaCo-ordinate with the relevant parties and contribute to the development of the monthly production schedule to enable timely material support to production, and to optimize the production of bulk drug substances so as to minimize holding costs of intermediate goods.Assess situation, plan and implement all process campaign turnaround activities, as well as co-ordinate and track progress of shift teams to ensure production plan adherence.Identify and implement improvement to plant facilities, processes, methods of operations and turnaround, as well as troubleshoot for process and equipment problems to minimize safety and quality risk; embracing a culture of continuous improvement that increases operational efficiency.Lead or support quality or safety related investigation using appropriate problem-solving tools to determine the root causes and implement CAPA to prevent recurrenceInitiate, coordinate, plan and participate in plant modification activities, as well as, plan and participate in the implementation of validation works, project commissioning, tie-in and/or capital projects.Conducts audits and investigations, as well as, participate in audit preparation in the assigned work area(s) to ensure compliance with GMP and Environmental, Health and Safety requirements.Prepare documents relating to plan turnaround, Local Operating Instructions (LOI), Local Standard Operating Procedures (SOP) and training manual to ensure that updated documents are in place and in use to support the activities of the operations department, schedule plan orders, and materials assignment.Support the Manager in plant trials, prepare and complete all necessary documents related to plant trial within the stipulated timeline.Plan and schedule waste management activities (includes solvent recovery and waste disposal) to ensure safe and effective waste management by staff.Provide M-ERP support as BPE if assigned.Ensure availability of equipment, tools, production consumables and follow up on ensuring housekeeping of the manufacturing facility.Prepare documents for decommissioning of facility and systemSkills, Knowledge & ExperienceGood honours degree in Chemistry or Chemical Engineering3 years of relevant experience in pharmaceutical, chemical or petro-chemicalKnowledge of product, production processes and the plantBasic engineering knowledgeBasic statistical knowledgeGood troubleshooting skillsKnowledge of GMP, safety, hygiene and environment regulationsTo learn more about Singapore GSK and our people, please click on this link:#Li-GSKWhy GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a special purpose \xe2\x80\x93 to unite science, technology and talent to get ahead of disease together \xe2\x80\x93 so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns \xe2\x80\x93 as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it\xe2\x80\x99s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves \xe2\x80\x93 feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK\'s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

GlaxoSmithKline