Job Description

The National University of Singapore invites applications for a Post-Doctoral Research Fellow on antibody engineering and nanobody design in the Infectious Diseases Translational Research Programme (ID TRP) and the Department of Biochemistry, Yong Loo Lin School of Medicine. ID TRP and Biochemistry are pooling efforts of prominent scientists from multiple disciplines and committed to human infectious diseases closely relevant to Singapore and the region. The project is carried out in close collaboration with other Translational Research Programmes, National University Hospital and National Centre for Infectious Diseases.

Appointments will be made on a two-year contract basis with the possibility of extension. The University, Programme and Department provide customised trainings and grant opportunities for early career researchers.

Purpose of the post

Working in the group of Assistant Professor QU Kun at the ID TRP and the Department of Biochemistry (), the Research Fellow will conduct a project aimed at studying the structure and function of virus transmission and neutralisation. The Qu lab is funded by the start-up award of the NUS Presidential Young Professorship and NMRC Young Individual Research Grant. We visualise dynamic and elusive viral infection processes in situ or in vitro using Cryo-Electron Tomography and subtomogram averaging. Main Duties and Responsibilities

The Research Fellow is expected to:

• Carry out scientific research aimed at understanding the synergy and dynamics of antibodies during virus infection;
• Introduce and apply a wide range of techniques in biochemistry and structural biology to prepare lipid vesicles and study antigen-antibody interactions;
• Present scientific work at internal meetings and external conferences;
• Draft scientific manuscripts and prepare high-quality images for publication;
• Contribute to scientific discussions and assist with other duties in the lab;
• Interact and collaborate with other members within the research team, across the programme, and from external groups;
• Maintain high standard of professional conduct and record keeping in accordance with scientific integrity, biosafety policies and procedures;
• Report to and discuss with the PI to ensure the project is performed in accordance with good practice.

Qualifications

The applicant must or should:

• Behave with scientific integrity and honesty;
• Hold a Ph.D. in Biochemistry, Molecular Biology, Immunology or related disciplines, or due to complete Ph.D. within 6 months;
• Have excellent expertise in multiple molecular biology techniques and structural biology methods, including endogenous protein purification, X-ray crystallography and single particle Cryo-EM;
• Have hands-on experience with mammalian and amphibian animal work including subcutaneous injection, blood draw, antibody identification and purification;
• Be able to work independently and be passionate about science;
• Be able to communicate and work with others in an open manner.

Remuneration will be commensurate with the candidate\'s qualifications and experience. For full consideration, please submit the cover letter, CV, names and contact information of 3 references to Dr QU Kun (***@nus.edu.sg) and Ms Mayvien Teo (). Only shortlisted candidates will be notified. -

Additional Information

Career Level

Not Specified

Qualification

Not Specified

Job Type

Full-Time

Job Specializations

,

Singapore Post