Offer Description
The Mechanobiology Institute (MBI), National University of Singapore is seeking to recruit a Research Fellow (RF) to join Dr. Gianluca Grenci\'s group, in the framework of a collaborative project with partners from A-STAR and IMRE. The project aims at studying the lipids content in tissue samples and live cells and their correlation with different conditions: \xe2\x80\x9cyoung\xe2\x80\x9d and \xe2\x80\x9caged\xe2\x80\x9d tissues and different dietary regimes. To this task, we are developing a methodology based on two original elements: we make use of a quantum IR microscope of our own design instead of a standard FTIR IR microscope and we are developing a new kind of microfluidic devices compatible with Vis/IR/UV microscopy for maintaining the live the samples during observation. For more details on these two key aspects and their working principles please refer to [1, 2].
The newly hired RF will be in charge of preparing the biological samples, conducting the characterization and chemical mapping with the quantum IR microscope and analyze the results with the scope of identify markers of different conditions and their possible correlations with pathological outcomes. Since microfluidic devices will be part of the experimental set-up to optimize, familiarity with this technology will be considered as a plus. MBI provides state-of-the-art core facilities both for biological samples preparation and for micro/nano fabrication for biological applications. * Paterova, A.V., Maniam, S.M., Yang, H., Grenci, G., Krivitsky, L.A., Hyperspectral infrared microscopy with visible light (2020) Science Advances, 6 (44), art. no. abd0460
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