Job Description

Company DescriptionTravecta Therapeutics is a preclinical stage biotech founded to advance neurological therapies through better brain targeting. The blood brain barrier is the protective barrier of the central nervous system and blocks 100% of large molecules and more than 98% of all small molecule drugs and is a main obstacle to therapeutics for brain diseases. The company's proprietary platform of transporter-enabled drug conjugates enhances brain access for multiple drug classes and provides multiple therapeutic development opportunities. A robust pipeline is leading to IND filing and further opportunities through pharma collaborations.This is an exciting role with high visibility within the company. Reporting directly to the Senior Director of R&D, this person will be responsible for directing all preclinical efficacy bioassays and pharmacokinetic studies. We are seeking a highly motivated individual looking for a full-time role for a period of 3-6 months with the possibility for the role to become a permanent position.The Associate Director / Director of Pharmacology role requires a scientific background with research and development experience in the pharmaceutical and/or biotech industry. This position has a critical role in selecting, prioritizing, and designing the projects to populate the development pipeline. The Director of Pharmacology will have experience in preclinical mechanistic and studies, guiding receptor/ion channel screens, in vitro and in vivoefficacy models as well as pharmacokinetic study design and assessment.The ideal candidate possesses a strong interest in innovative technology and advances to deliver innovative and competitive solutions to pharmacologic problems. They are a strategic and creative thinker who shows excellent problem-solving and communication skills and can network effectively. They should have the drive and ability to independently seek solutions in the literature and consultant network to proactively solve pharmacologic challenges and advance the company's programs. They should have ability and experience to present complicated scientific concepts to internal and external collaborators in an individual or group setting.Key Responsibilities

• Design and implement in vitro and in vivopharmacology and pharmacokinetic protocols and projects.
• Review and assess all pharmacokinetic and pharmacodynamic data; analyse data independently and report results and actions to management
• Engage and manage external contracting and consulting resources as needed.
• Provide focus to individual team members
• Establish and monitor timelines to ensure efficient delivery of data.
• Represent departmental interests in internal and external communication.
• Execute advanced analytical techniques to extend scientific theories in innovative pharmacology projects.
• Utilize diverse knowledge of scientific research principles, practices and protocols in research projects.
• Recommend early development strategies to support corporate goals.Minimum Knowledge/ Education / Previous Experience requirement
• PhD or equivalent advanced degree in pharmacology or a relevant biological discipline.
• At least 5 years of experience in pre-clinical development of innovative drugs in Pharmaceutical / Life Science / Biotech / CRO settings.
• A strategic thinker with an understanding of the practical realities and priorities of pharmaceutical discovery and development.
• Experience in PK/PD modelling, cellular pharmacology assays, in vivo pharmacology and pharmacodynamic models.
• Experience designing and interpreting IND-enabling toxicology and safety studies.
• Experience in strategic planning for target selection, direction of CRO partners and management of internal staff.
• Strong written and verbal communication skills and possessing the ability to present and explain highly technical topics to broad audiences.
• A performance-driven individual, with a strong sense of urgency and credibility.